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PD-1 Antikörper (Internal Region)

Name: PD-1 Antikörper (Internal Region)
SKU: ABIN374561
Price: 714.15 EUR
Availability: InStock

PDCD1 Reaktivität: Human, Maus, Ratte, Hund WB Wirt: Ziege Polyclonal unconjugated

Image no. 2 for anti-Programmed Cell Death 1 (PDCD1) (Internal Region) antibody (ABIN374561) (PD-1 Antikörper (Internal Region))

Image no. 1 for anti-Programmed Cell Death 1 (PDCD1) (Internal Region) antibody (ABIN374561) (PD-1 Antikörper (Internal Region))

2 Abbildungen

Produktnummer ABIN374561

Datenblatt (PDF)

Target Alle PD-1 (PDCD1) Antikörper anzeigen

PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
Bindungsspezifität
16

8

5

5

4

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Internal Region
Reaktivität
143

83

25

5

3

1
Human, Maus, Ratte, Hund
Wirt
73

70

34

12

9

3

3

1
Ziege
Passende Sekundärantikörper
Klonalität
146

56

2
Polyklonal
Konjugat
94

16

13

12

7

6

5

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser PD-1 Antikörper ist unkonjugiert
Applikation
131

59

46

41

34

17

13

13

13

10

10

9

9

8

6

5

4

4

3

3

3

3

3

3

2

2

2

1

1

1
Western Blotting (WB)

Spezifität

This antibody recognizes Programmed Cell Death 1 (CD279/PDCD1).

Kreuzreaktivität (Details)

Species reactivity (expected):Mouse, Rat, Canine (Dog) and Bovine.
Species reactivity (tested):Human.

Aufreinigung

Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen

Synthetic Peptide (C-GELDFQWREKTPE) from an internal region of Human CD279.

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PDCD1 Reaktivität: Human IHC, ELISA, StM, Coat Wirt: Maus Monoclonal PDCD1-2720 unconjugated

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PDCD1 Reaktivität: Human, Non-Human Primate FACS, IHC (fro) Wirt: Maus Monoclonal EH12-2H7 unconjugated

Applikationshinweise

Peptide ELISA: Detection Limit Dilution: 1/16000. Western Blot: 0.5-1.5 μg/mL. Approx 28-30 kDa band observed in Human Bone Marrowlysates (calculated MW of 31.0 kDa according to NP_005009.1). Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.5 mg/mL

Buffer

Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target

PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung

CD279 / PD1 (PDCD1 Produkte)

Synonyme

CD279 antikoerper, PD-1 antikoerper, PD1 antikoerper, SLEB2 antikoerper, hPD-1 antikoerper, hPD-l antikoerper, Ly101 antikoerper, Pdc1 antikoerper, programmed cell death 1 antikoerper, PDCD1 antikoerper, Pdcd1 antikoerper

Hintergrund

CD279 is an immunoglobulin superfamily member, also known as Programmed Cell Death 1. Programmed Cell Death 1 is expressed on a subset of CD4-CD8 thymocytes, and on activated T and B cells. Programmed Cell Death 1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The Programmed Cell Death 1 ligands, PDL1 (also known as B7H1) and PDL2 (B7DC), are members of the B7 immunoglobulin superfamily.Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1

Gen-ID

5133, 9606

UniProt

Q15116

Pathways

Cancer Immune Checkpoints