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CD14 Antikörper (Internal Region)

Name: CD14 Antikörper (Internal Region)
SKU: ABIN374645
Price: 810.93 EUR
Availability: InStock

CD14 Reaktivität: Human WB, IHC (p), EIA Wirt: Ziege Polyclonal unconjugated

Image no. 2 for anti-CD14 (CD14) (Internal Region) antibody (ABIN374645) (CD14 Antikörper (Internal Region))

Image no. 1 for anti-CD14 (CD14) (Internal Region) antibody (ABIN374645) (CD14 Antikörper (Internal Region))

2 Abbildungen

Produktnummer ABIN374645

Datenblatt (PDF)

Target Alle CD14 Antikörper anzeigen

CD14
Bindungsspezifität
9

6

5

5

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Internal Region
Reaktivität
254

45

40

27

25

23

23

23

20

17

16

15

14

14

13

10

8

7

6

5

5

2

1

1
Human
Wirt
227

52

25

3

1
Ziege
Passende Sekundärantikörper
Klonalität
254

54
Polyklonal
Konjugat
124

34

25

20

15

8

6

5

5

5

5

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD14 Antikörper ist unkonjugiert
Applikation
232

87

65

57

56

50

22

16

13

12

7

6

4

4

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz

C-KRVDADADPR QYAD

Spezifität

This antibody recognizes CD14.

Kreuzreaktivität (Details)

Species reactivity (tested):Human.

Aufreinigung

Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen

Peptide with sequence from the internal region of the protein sequence according to NP_000582.1. Genename: CD14

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Applikationshinweise

Peptide ELISA: 1/128000. Western Blot: 1 - 3 μg/mL. Immunohistochemistry on paraffin sections: 4 - 6 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.5 mg/mL

Buffer

Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target

CD14

Andere Bezeichnung

CD14 (CD14 Produkte)

Synonyme

CD14 molecule antikoerper, CD14 antigen antikoerper, CD14 antikoerper, Cd14 antikoerper

Hintergrund

CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

Gen-ID

929, 9606

UniProt

P08571

Pathways

TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades