Ezrin Antikörper (Internal Region)
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- Target Alle Ezrin (EZR) Antikörper anzeigen
- Ezrin (EZR)
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Hund
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser Ezrin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Sequenz
- C-QDYEEKTKKA ER
- Spezifität
- This antibody reacts to Ezrin / villin 2.
- Kreuzreaktivität (Details)
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Species reactivity (expected):Canine.
Species reactivity (tested):Human. - Aufreinigung
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
- Immunogen
- Peptide with sequence from the internal region of the protein sequence according to NP_003370.2. Genename: VIL2
- Top Product
- Discover our top product EZR Primärantikörper
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- Applikationshinweise
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ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Ezrin (EZR)
- Andere Bezeichnung
- Ezrin (EZR Produkte)
- Hintergrund
- Ezrin (also known as p81, 80K, or cytovillin) is a cytoplasmic protein which is enriched in microvilli and other cell surface structures. Its NH2-terminal domain is associated with the plasma membrane and the COOH-terminal domain with the cytoskeleton. Ezrin has an actin-binding capability. Ezrin is expressed in epithelial cells but not in mesenchymal cells. Ezrin is also expressed by certain epithelial tumors, such as renal cell adenocarcinomas. Ezrin serves as a tyrosine kinase substrate, and is phosphorylated in EGF-stimulated cells.Synonyms: Cytovillin, EZR, VIL2, Villin-2, p81
- Gen-ID
- 7430, 9606
- UniProt
- P15311
- Pathways
- Maintenance of Protein Location
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