GPX4 Antikörper (C-Term, Isoform A)
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- Target Alle GPX4 Antikörper anzeigen
- GPX4 (Glutathione Peroxidase 4 (GPX4))
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Bindungsspezifität
- C-Term, Isoform A
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Schwein
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser GPX4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody is expected to recognize isoform A (NP_002076.2) and isoform C (NP_001034937.1).
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse, Rat, Pig, Cow.
Species reactivity (tested):Human. - Aufreinigung
- Affinity Chromatpography
- Immunogen
- Peptide with sequence (C-EEPLVIEKDLPHY) from the C-terminus of the protein sequencen (NP_002076.2, NP_001034937.1).
- Top Product
- Discover our top product GPX4 Primärantikörper
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- Applikationshinweise
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ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL. Immunohistochemistry on paraffin sections: 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- GPX4 (Glutathione Peroxidase 4 (GPX4))
- Andere Bezeichnung
- Glutathione Peroxidase 4 / GPX4 (GPX4 Produkte)
- Synonyme
- GPx-4 antikoerper, GSHPx-4 antikoerper, MCSP antikoerper, PHGPx antikoerper, snGPx antikoerper, snPHGPx antikoerper, Phgpx antikoerper, gpx-4 antikoerper, snGpx antikoerper, cb563 antikoerper, cb691 antikoerper, PHGPxa antikoerper, sb:cb563 antikoerper, zgc:92253 antikoerper, wu:fb82e03 antikoerper, 1700027O09Rik antikoerper, mtPHGPx antikoerper, ATGPX4 antikoerper, F11L15.5 antikoerper, glutathione peroxidase 4 antikoerper, GP-GPx4 antikoerper, glutathione peroxidase 4 antikoerper, glutathione peroxidase 4a antikoerper, GPX4 antikoerper, Gpx4 antikoerper, gpx4a antikoerper
- Hintergrund
- Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.Synonyms: GPx-4, Phospholipid hydroperoxide glutathione peroxidase mitochondrial
- Gen-ID
- 2879
- NCBI Accession
- NP_001034936
- UniProt
- P36969
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