NPY2R Antikörper (Internal Region)

Produktnummer ABIN374839

Produktdetails anti-NPY2R Antikörper

Target: NPY2R (Neuropeptide Y Receptor Y2 (NPY2R))

Bindungsspezifität: Internal Region

Reaktivität: Maus, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser NPY2R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Neuropeptide Y receptor 2.

Kreuzreaktivität (Details): Species reactivity (expected):Canine (Dog).
Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence C-KAKKNLEVKKNN, from the internal region of the protein sequence Genename: Npy2r .Remarks: This antibody was designed using the Mouse sequence, which differs by 1 amino acid from the Human sequence.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Detection Limit: 1/32000. Western Blot: 0.1-0.3 μg/mL. Approx 40+45 kDa bands observed in Mouse Brain and RatBrain lysates (calculated MW of 42.5 kDa according to NP032757.1). A customer successfully used this product for immunoprecipitation of Human Y2R.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu NPY2R

Target: NPY2R (Neuropeptide Y Receptor Y2 (NPY2R))

Andere Bezeichnung: Neuropeptide Y Receptor 2 (NPY2R Produkte)

Hintergrund: Neuropeptide Y (NPY) receptors are members of a G protein coupled receptor superfamily and they mediate a variety of physiological responses including feeding and vasoconstriction. The endogenous ligands of NPY receptors are a family of structurally related peptides, including NPY, peptide YY (PYY), and pancreatic polypeptide (PP). Increased activity of NPY and its receptors, Y1R, Y2R, and Y5R has been found in the brain in many forms of experimental obesity. Furthermore, several association studies have supported the association between NPY2R and obesity.Synonyms: NPY-Y2 receptor, NPY2-R, Neuropeptide Y receptor 2, Y2 receptor

Gen-ID: 4887, 9606

UniProt: P49146

Pathways: cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour