FZD4 Antikörper (Internal Region)

Produktnummer ABIN374922

Produktdetails anti-FZD4 Antikörper

Target: FZD4 (Frizzled Family Receptor 4 (FZD4))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser FZD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to Frizzled 4.

Kreuzreaktivität (Details): Species reactivity (expected):Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence DEEERRCDPIRIS, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-FZD4 Antikörper (ABIN374922)

You, Nguyen, Albers, Lin, Holcombe: "Wnt pathway-related gene expression in inflammatory bowel disease." in: Digestive diseases and sciences, Vol. 53, Issue 4, pp. 1013-9, (2008) (PubMed).

Details zu FZD4

Target: FZD4 (Frizzled Family Receptor 4 (FZD4))

Andere Bezeichnung: CD344 / FZD4 / Frizzled-4 (FZD4 Produkte)

Hintergrund: Frizzled 4 is a member of the frizzled gene family. Members of this family encode seven transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.Synonyms: Fz-4, FzE4, hFz4

Gen-ID: 8322

NCBI Accession: NP_036325

UniProt: Q9ULV1

Pathways: WNT Signalweg, Hormone Transport, Sensory Perception of Sound