GRIK3
Reaktivität: Human
ELISA
Wirt: Maus
Monoclonal
4H1
unconjugated
Applikationshinweise
Peptide ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0,5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Chao, Chen, Liu: "S-allyl L-cysteine protects the retina against kainate excitotoxicity in the rat." in: The American journal of Chinese medicine, Vol. 42, Issue 3, pp. 693-708, (2014) (PubMed).
GRIK3 belongs to the ligand gated ionic channel family and is a receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of glutamate are mediated by a variety of receptors that are named according to their selective agonists. The GRIK3 receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA. GRIK3 can coassemble with either GRIK4 or GRIK5 to form heteromeric receptors. RNA editing in the mRNA has been reported.Synonyms: EAA5, Excitatory amino acid receptor 5, GluR-7, Glutamate receptor 7, Glutamate receptor ionotropic kainate 3