MBNL1 Antikörper (C-Term)
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- Target Alle MBNL1 Antikörper anzeigen
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Ratte, Maus, Hund, Rind (Kuh)
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser MBNL1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- This antibody reacts to MBNL1.
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human. - Aufreinigung
- Affinity chromatography
- Immunogen
- Peptide with sequence C-SAEHLTSHKYVTQ, from the C Terminus of the protein sequence
- Top Product
- Discover our top product MBNL1 Primärantikörper
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- Applikationshinweise
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Peptide ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0,5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
- Andere Bezeichnung
- MBNL1 (MBNL1 Produkte)
- Synonyme
- MBNL1 antikoerper, zgc:153954 antikoerper, Mbnl antikoerper, mKIAA0428 antikoerper, EXP antikoerper, EXP35 antikoerper, EXP40 antikoerper, EXP42 antikoerper, MBNL antikoerper, muscleblind like splicing regulator 1 antikoerper, muscleblind-like splicing regulator 1 antikoerper, muscleblind like splicing factor 1 antikoerper, MBNL1 antikoerper, mbnl1 antikoerper, Mbnl1 antikoerper
- Hintergrund
- Muscleblind 1 (MBNL1) binds to the CUG triplet expansion in dsRNA. It appears to play a role in RNA splicing. Several important human diseases are associated with expansion of polynucleotide sequences, in most cases trinucleotide repeats. Myotonic dystrophy (DM1) is one of these diseases, and is associated with increases in the number of CTG repeats in the 3' UTR of the gene encoding myotonin (a.k.a. DM Kinase, DMK or myotonin-Protein Kinase), a ser/thr kinase expressed specifically in muscle. Mammalian genomes contain three muscleblind-like proteins, generally referred to as MBNL1, MBNL2 and MBNL3, and all three were found to associate with long double stranded CUG RNA repeats, thus being triplet repeat expansion dsRNA-binding proteins.Synonyms: EXP, Muscleblind-like protein 1
- Gen-ID
- 4154, 9606
- UniProt
- Q9NR56
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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