MGLL Antikörper (Internal Region)

Produktnummer ABIN375108

Produktdetails anti-MGLL Antikörper

Target: MGLL (Monoglyceride Lipase (MGLL))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser MGLL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to Monoglyceride Lipase.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-QDLPHLVNADGQY, from the internal region (near NTerminus) of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-MGLL Antikörper (ABIN375108)

Blankman, Simon, Cravatt: "A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol." in: Chemistry & biology, Vol. 14, Issue 12, pp. 1347-56, (2007) (PubMed).

Details zu MGLL

Target: MGLL (Monoglyceride Lipase (MGLL))

Andere Bezeichnung: Monoglyceride Lipase (MGLL Produkte)

Hintergrund: Endocannaboids such as arachidonoyl ethanolamide and 2-arachidonoyl glycerol function as short range modulators of cell and synaptic activity. Monoacylglycerol lipase hydrolyzes 2-arachidonoyl glycerol which terminates it's biological actions. Monoacylglycerol lipase also works consecutively with hormone sensitive lipase to mobilize fatty acids from triglyceride stores of adipocytes. Monoacylglycerol lipase is expressed in kidney, spleen, heart, liver, testis, stomach, brain and lung tissue, and adrenal gland. It is most abundantly expressed in skeletal muscle and adipose tissue.Synonyms: HU-K5, Lysophospholipase homolog, Lysophospholipase-like, MGL, MGLL

Gen-ID: 11343, 9606

UniProt: Q99685

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Lipid Metabolism