TCRgd Antikörper (PE)

Produktnummer ABIN376497

Produktdetails

Target: TCRgd

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: PE

Applikation: Flow Cytometry (FACS)

Spezifität: Mouse TCR

Produktmerkmale: Hamster Anti-Mouse TCRgd-PE

Aufreinigung: Purified

Immunogen: Mouse T cell clone G8

Klon: UC7-13D5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IP - Reported in literature , Costim - Reported in literature , Depletion - Reported in literature
• Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE and SPRD conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Kommentare:

In vivo depletion of gd TCR-expressing T cell

Probenmenge: 2 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/Sodium azide and a stabilizing agent

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Antigendetails

Target: TCRgd

Hintergrund: The TCR γδ heterodimer of the CD3/T-cell receptor complex is clonotypic and consists of Ig-like variable and constant domains. It is expressed during thymopoiesis and on the small subpopulation of γδ TCR- expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are γδ + and have limited receptor diversity. The TCR γδ heterodimer recognizes peptide antigen bound to MHC antigens, and subsequent signal transduction mediated by the invariant chains leads to T cell activation.