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IL2 Receptor beta Antikörper (PE)

IL2RB Reaktivität: Maus FACS Wirt: Ratte Monoclonal 5H4 PE
Produktnummer ABIN376503
  • Target Alle IL2 Receptor beta (IL2RB) Antikörper anzeigen
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    Reaktivität
    • 94
    • 85
    • 16
    • 5
    • 1
    Maus
    Wirt
    • 78
    • 37
    • 26
    Ratte
    Klonalität
    • 79
    • 61
    • 1
    Monoklonal
    Konjugat
    • 62
    • 14
    • 11
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL2 Receptor beta Antikörper ist konjugiert mit PE
    Applikation
    • 71
    • 71
    • 32
    • 26
    • 26
    • 19
    • 16
    • 10
    • 9
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Mouse CD122, 90-100 kDa
    Produktmerkmale
    Rat Anti-Mouse CD122-PE
    Aufreinigung
    Purified
    Immunogen
    Rat myeloma YB2/0 transfected with truncated IL-2Rbeta cDNA (YB2/0-mbetat-28)
    Klon
    5H4
    Isotyp
    IgG2a
    Top Product
    Discover our top product IL2RB Primärantikörper
  • Applikationshinweise
    • Applications: FC - Quality tested , IP - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE and APC conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Probenmenge
    1 mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg/mL
    Buffer
    0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C
  • Target
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    Andere Bezeichnung
    CD122 (IL2RB Produkte)
    Synonyme
    IL2RB antikoerper, il-2rb antikoerper, CD122 antikoerper, IL15RB antikoerper, P70-75 antikoerper, IL2RBC antikoerper, IL-15Rbeta antikoerper, IL15Rbeta antikoerper, Il-2/15Rbeta antikoerper, Il-2Rbeta antikoerper, p70 antikoerper, interleukin 2 receptor subunit beta antikoerper, interleukin-2 receptor subunit beta antikoerper, interleukin 2 receptor, beta antikoerper, interleukin 2 receptor, beta chain antikoerper, IL2RB antikoerper, LOC510185 antikoerper, il2rb antikoerper, Il2rb antikoerper
    Hintergrund
    The IL-2 receptor is a complex of three distinct polypeptide chains: (i) the α chain which binds IL-2 with low affinity, (ii) the β chain that binds IL-2 with high affinity, and (ii) the common γ chain ( γ C ) that does not bind IL-2. The high affinity receptor complex is an α / β / γ heterotrimer with a K d of 1.3 x 10 -11 M. In mouse spleen, CD122 is expresed on approx. 30 % of CD8 + cells and all NK cells, but < 1 % of B cells and CD4 + T lymphocytes. In the thymus, its expression is confined to CD4 - CD8 + single positive and CD4 - CD8 - double negative cells. Cytoplasmic regions of the IL-2R β chain are involved in IL-2-mediated cellular signaling and, via the interaction of IL-2 and its receptor complex, may be involved in the generation and differentiation of T lymphocytes.
    Pathways
    JAK-STAT Signalweg, Growth Factor Binding
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