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CD11b Antikörper

ITGAM Reaktivität: Ratte IHC, IHC (fro) Wirt: Maus Monoclonal OX-42 unconjugated

Produktnummer ABIN380068

Datenblatt (PDF)

Target Alle CD11b (ITGAM) Antikörper anzeigen

CD11b (ITGAM) (Integrin alpha M (ITGAM))
Reaktivität
282

175

72

34

20

19

17

14

11

10

7

4

4

2

2

1
Ratte
Wirt
160

115

107

2

1

1
Maus
Passende Sekundärantikörper
Klonalität
287

96

1
Monoklonal
Konjugat
126

39

33

29

22

11

8

8

7

7

6

6

5

5

4

4

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Dieser CD11b Antikörper ist unkonjugiert
Applikation
287

87

86

83

63

50

39

22

22

21

14

14

12

6

5

5

5

4

3

2

2

2

2

2

1

1

1

1
Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität

CD11b/c. OX-42 recognizes three major polypeptides of 160  kDa, 103  kDa and 95  kDa and a minor 133  kDa protein under non-reducing conditions. Under reducing conditions two major peptides of 163  kDa and 100  kDa and a minor 135  kDa peptide are detected. Antigen distribution: Isolated cells: OX-42 shows a similar reaction pattern to OX-41 on various isolated cells but stains bronchial lavage cells to a lesser degree. OX-42 inhibits complement mediated rosettes. Tissue sections: OX-42 is a most suitable marker for the identification of microglial cells and Kupffer cells. It also stains dendritic cells strongly. Only a subpopulation of alveolar macrophages is recognised. Specificity: Rat: granulocytes, macrophages, microglial cells. Other species: not tested

Aufreinigung

Purified

Immunogen

Peritoneal macrophages

Klon

OX-42

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Applikationshinweise

Approved: IHC, IHC-Fr (1:100 - 1:200)

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

PBS  pH 7.2, 0.09 % sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C.
Target

CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung

CD11b + C (ITGAM Produkte)

Hintergrund

Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

Gen-ID

3684

Pathways

Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation