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c-MET Antikörper (Catalytic Domain)

Name: c-MET Antikörper (Catalytic Domain)
SKU: ABIN387741
Price: 445.5 EUR
Availability: InStock

MET Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Maus Monoclonal 4AT44 unconjugated

All lanes : Anti-MET/HGFR Antibody at dilution Lane 1: HeLa whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: COS-7 whole cell lysate Lysates/proteins at 20 μg per lane. (c-MET Antikörper (Catalytic Domain))

Immunohistochemical analysis of paraffin-embedded H. (c-MET Antikörper (Catalytic Domain))

IHC (p)

Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with MET/HGFR Antibody (ABIN387741 and ABIN2837999) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (c-MET Antikörper (Catalytic Domain))

IHC (p)

3 Abbildungen

Produktnummer ABIN387741

Datenblatt (PDF)

Target Alle c-MET (MET) Antikörper anzeigen

c-MET (MET) (Met Proto-Oncogene (MET))
Bindungsspezifität
42

28

28

28

12

11

7

7

7

7

6

5

4

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Catalytic Domain
Reaktivität
228

132

102

6

6

5

4

4

2

2

2

1

1

1

1
Human, Maus
Wirt
201

37

3

2
Maus
Passende Sekundärantikörper
Klonalität
197

46
Monoklonal
Konjugat
126

19

11

11

7

7

7

7

7

7

6

6

2

2

2

2

2

2

2

2

2

2

2
Dieser c-MET Antikörper ist unkonjugiert
Applikation
160

102

43

28

26

18

15

14

12

9

8

5

4

4

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen

This monoclonal antibody is generated from mice immunized with purified recombinant protein encoding the catalytic domain of human Met.

Klon

4AT44

Isotyp

IgG1

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Applikationshinweise

IF: 1:100. WB: 1:8000. IHC-P: 1:50~100. IHC-P: 1:25

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid freeze-thaw cycles.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Haltbarkeit

6 months
Target

c-MET (MET) (Met Proto-Oncogene (MET))

Andere Bezeichnung

MET/HGFR (MET Produkte)

Synonyme

AUTS9 antikoerper, HGFR antikoerper, RCCP2 antikoerper, c-Met antikoerper, AI838057 antikoerper, HGF antikoerper, Par4 antikoerper, Hgfr antikoerper, c-met antikoerper, MET antikoerper, C-MET antikoerper, met antikoerper, met-A antikoerper, MET proto-oncogene, receptor tyrosine kinase antikoerper, met proto-oncogene antikoerper, MET proto-oncogene, receptor tyrosine kinase L homeolog antikoerper, MET antikoerper, Met antikoerper, met.L antikoerper

Hintergrund

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

155541

Gen-ID

4233

NCBI Accession

NP_000236, NP_001120972

UniProt

P08581

Pathways

RTK Signalweg, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor