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Dnmt2 Antikörper (AA 346-375)

TRDMT1 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB1850 unconjugated
Produktnummer ABIN387859
  • Target Alle Dnmt2 (TRDMT1) Antikörper anzeigen
    Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
    Bindungsspezifität
    • 15
    • 12
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 346-375
    Reaktivität
    • 72
    • 23
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 67
    • 7
    Kaninchen
    Klonalität
    • 69
    • 5
    Polyklonal
    Konjugat
    • 30
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Dnmt2 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 42
    • 31
    • 13
    • 13
    • 7
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This Dnmt2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from human Dnmt2.
    Klon
    RB1850
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product TRDMT1 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Lee, Jang, Benoit, Hoque, Califano, Trink, Sidransky, Mao, Moon: "Presence of 5-methylcytosine in CpNpG trinucleotides in the human genome." in: Genomics, Vol. 96, Issue 2, pp. 67-72, (2010) (PubMed).

  • Target
    Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
    Andere Bezeichnung
    Dnmt2 (TRDMT1 Produkte)
    Synonyme
    MGC89267 antikoerper, DMNT2 antikoerper, DNMT2 antikoerper, MHSAIIP antikoerper, PUMET antikoerper, RNMT1 antikoerper, Dnmt2 antikoerper, Rnmt2 antikoerper, dnmt2 antikoerper, tRNA aspartic acid methyltransferase 1 antikoerper, tRNA aspartic acid methyltransferase 1 L homeolog antikoerper, trdmt1 antikoerper, TRDMT1 antikoerper, Trdmt1 antikoerper, trdmt1.L antikoerper
    Hintergrund
    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Molekulargewicht
    44597
    Gen-ID
    1787
    NCBI Accession
    NP_004403
    UniProt
    O14717
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