Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

JMJD2D Antikörper (C-Term)

KDM4D Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB10797 unconjugated
Produktnummer ABIN387871
  • Target Alle JMJD2D (KDM4D) Antikörper anzeigen
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    Bindungsspezifität
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 484-516, C-Term
    Reaktivität
    • 33
    • 3
    • 2
    • 1
    Human
    Wirt
    • 33
    Kaninchen
    Klonalität
    • 33
    Polyklonal
    Konjugat
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser JMJD2D Antikörper ist unkonjugiert
    Applikation
    • 22
    • 18
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This JMJD2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-516 amino acids from the C-terminal region of human JMJD2D.
    Klon
    RB10797
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product KDM4D Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    Andere Bezeichnung
    JMJD2D (KDM4D Produkte)
    Synonyme
    JMJD2D antikoerper, 4932416A15 antikoerper, Jmjd2d antikoerper, KDM4D antikoerper, lysine demethylase 4D antikoerper, lysine-specific demethylase 4D antikoerper, lysine (K)-specific demethylase 4D antikoerper, KDM4D antikoerper, LOC524768 antikoerper, Kdm4d antikoerper, LOC617971 antikoerper, LOC100067461 antikoerper, LOC698455 antikoerper, LOC100514356 antikoerper
    Hintergrund
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
    Molekulargewicht
    58603
    Gen-ID
    55693
    NCBI Accession
    NP_060509
    UniProt
    Q6B0I6
    Pathways
    Warburg Effekt
Sie sind hier:
Kundenservice