This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This SETDB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1193-1225 amino acids from the C-terminal region of human SETDB1.
ESET antikoerper, H3-K9-HMTase4 antikoerper, KG1T antikoerper, KMT1E antikoerper, TDRD21 antikoerper, AU022152 antikoerper, mKIAA0067 antikoerper, SETDB1 antikoerper, NV10069 antikoerper, fc07d03 antikoerper, si:ch211-81a5.6 antikoerper, wu:fc07d03 antikoerper, im:7143091 antikoerper, wu:fa04a12 antikoerper, wu:fj80h02 antikoerper, zgc:152899 antikoerper, SET domain bifurcated 1 antikoerper, SET domain, bifurcated 1 antikoerper, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 antikoerper, histone-lysine N-methyltransferase SETDB1 antikoerper, SET domain, bifurcated 1a antikoerper, SET domain bifurcated 1 L homeolog antikoerper, SET domain, bifurcated 1b antikoerper, SETDB1 antikoerper, Setdb1 antikoerper, MLLT11 antikoerper, LOC100120014 antikoerper, LOC100461671 antikoerper, setdb1a antikoerper, setdb1.L antikoerper, setdb1b antikoerper
Hintergrund
The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and 'Enhancer of zeste' proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities.