HAT1 Antikörper (C-Term)

Produktnummer ABIN387932

Produktdetails anti-HAT1 Antikörper

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Bindungsspezifität: AA 389-419, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This KAT1 (HAT1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-419 amino acids from the C-terminal region of human KAT1 (HAT1).

Klon: RB5769

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:100. IHC-P: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu HAT1

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Andere Bezeichnung: KAT1 (HAT1) (HAT1 Produkte)

Synonyme: KAT1 antikoerper, HAC07 antikoerper, HAC7 antikoerper, HAG02 antikoerper, MIK19.19 antikoerper, MIK19_19 antikoerper, histone acetyltransferase of the GNAT family 2 antikoerper, hac106 antikoerper, hat1 antikoerper, zgc:92639 antikoerper, histone acetyltransferase 1 antikoerper, histone acetyltransferase of the GNAT family 2 antikoerper, histone acetyltransferase catalytic subunit antikoerper, histone acetyltransferase Hat1 antikoerper, histone acetyltransferase 1 L homeolog antikoerper, HAT1 antikoerper, Hat1 antikoerper, HAG2 antikoerper, hat1 antikoerper, hat1.L antikoerper

Hintergrund: Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to a lesser extent, histone H2A at lys5. HAT1 and p46 polypeptides are located in the nucleus of S-phase cells. HAT1 may play a role in telomeric silencing.

Molekulargewicht: 49513

Gen-ID: 8520

NCBI Accession: NP_003633

UniProt: O14929