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HDAC11 Antikörper (N-Term)

HDAC11 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB2588 unconjugated
Produktnummer ABIN387964
  • Target Alle HDAC11 Antikörper anzeigen
    HDAC11 (Histone Deacetylase 11 (HDAC11))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reaktivität
    • 48
    • 43
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 58
    • 5
    Kaninchen
    Klonalität
    • 60
    • 3
    Polyklonal
    Konjugat
    • 36
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HDAC11 Antikörper ist unkonjugiert
    Applikation
    • 53
    • 33
    • 22
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This HDAC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HDAC11.
    Klon
    RB2588
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Janssen, Schmalbach, Boeselt, Sarlette, Dengler, Petri: "Differential histone deacetylase mRNA expression patterns in amyotrophic lateral sclerosis." in: Journal of neuropathology and experimental neurology, Vol. 69, Issue 6, pp. 573-81, (2010) (PubMed).

  • Target
    HDAC11 (Histone Deacetylase 11 (HDAC11))
    Andere Bezeichnung
    HDAC11 (HDAC11 Produkte)
    Synonyme
    CG31119 antikoerper, DHDACX antikoerper, Dmel\\CG31119 antikoerper, HDAC11 antikoerper, HDACX antikoerper, dHDAC11 antikoerper, dmHDA403 antikoerper, zgc:91942 antikoerper, HD11 antikoerper, histone deacetylase 11 antikoerper, Histone deacetylase 11 antikoerper, hypothetical protein antikoerper, HDAC11 antikoerper, hdac11 antikoerper, CpipJ_CPIJ001619 antikoerper, Bm1_15905 antikoerper, LOAG_18214 antikoerper, Hdac11 antikoerper
    Hintergrund
    HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.
    Molekulargewicht
    39183
    Gen-ID
    79885
    NCBI Accession
    NP_001129513, NP_079103
    UniProt
    Q96DB2
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