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KDM3A Antikörper (N-Term)

KDM3A Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB14307 unconjugated
Produktnummer ABIN387995
  • Target Alle KDM3A Antikörper anzeigen
    KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))
    Bindungsspezifität
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-79, N-Term
    Reaktivität
    • 37
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 24
    • 13
    Kaninchen
    Klonalität
    • 24
    • 13
    Polyklonal
    Konjugat
    • 27
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KDM3A Antikörper ist unkonjugiert
    Applikation
    • 27
    • 16
    • 16
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This JHDM2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human JHDM2a.
    Klon
    RB14307
    Isotyp
    Ig Fraction
    Top Product
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  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))
    Andere Bezeichnung
    JHDM2a (KDM3A Produkte)
    Hintergrund
    JHDM2a is a zinc finger protein that contains a jumonji domain. It is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. This protein preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. It is involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation.
    Molekulargewicht
    147341
    Gen-ID
    55818
    NCBI Accession
    NP_001140160, NP_060903
    UniProt
    Q9Y4C1
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Warburg Effekt
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