KDM3A Antikörper (N-Term)

Produktnummer ABIN387995

Produktdetails anti-KDM3A Antikörper

Target: KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

Bindungsspezifität: AA 50-79, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This JHDM2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human JHDM2a.

Klon: RB14307

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu KDM3A

Target: KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

Andere Bezeichnung: JHDM2a (KDM3A Produkte)

Synonyme: JHDM2A antikoerper, JHMD2A antikoerper, JMJD1 antikoerper, JMJD1A antikoerper, TSGA antikoerper, tsga antikoerper, jmjd1 antikoerper, jhdm2a antikoerper, jhmd2a antikoerper, jmjd1a antikoerper, 1700105C21Rik antikoerper, C230043E16Rik antikoerper, JHDM2a antikoerper, Jmjd1 antikoerper, Jmjd1a antikoerper, KDM2A antikoerper, TGSA antikoerper, Tsga antikoerper, mKIAA0742 antikoerper, KDM3A antikoerper, kdm3a antikoerper, lysine demethylase 3A antikoerper, lysine (K)-specific demethylase 3A antikoerper, lysine-specific demethylase 3A antikoerper, lysine (K)-specific demethylase 3A S homeolog antikoerper, KDM3A antikoerper, kdm3a antikoerper, Kdm3a antikoerper, LOC100453519 antikoerper, kdm3a.S antikoerper

Hintergrund: JHDM2a is a zinc finger protein that contains a jumonji domain. It is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. This protein preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. It is involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation.

Molekulargewicht: 147341

Gen-ID: 55818

NCBI Accession: NP_001140160, NP_060903

UniProt: Q9Y4C1

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Warburg Effekt