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SENP2 Antikörper (C-Term)

SENP2 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB2705 unconjugated
Produktnummer ABIN388045
  • Target Alle SENP2 Antikörper anzeigen
    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 502-533, C-Term
    Reaktivität
    • 38
    • 31
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus
    Wirt
    • 47
    • 7
    Kaninchen
    Klonalität
    • 47
    • 7
    Polyklonal
    Konjugat
    • 25
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SENP2 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 19
    • 17
    • 13
    • 13
    • 12
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This SENP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 502-533 amino acids from the C-terminal region of human SENP2.
    Klon
    RB2705
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SENP2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Maruyama, Lin, Chiu, Yu, Porter, Hsu: "Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development." in: Scientific reports, Vol. 6, pp. 20999, (2016) (PubMed).

    La Salle, Sun, Zhang, Matunis, Handel: "Developmental control of sumoylation pathway proteins in mouse male germ cells." in: Developmental biology, Vol. 321, Issue 1, pp. 227-37, (2008) (PubMed).

  • Target
    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
    Andere Bezeichnung
    SENP2 (SENP2 Produkte)
    Synonyme
    2310007L05Rik antikoerper, 4930538C18Rik antikoerper, AI646780 antikoerper, AW554757 antikoerper, Smt3ip2 antikoerper, SuPr-1 antikoerper, mKIAA1331 antikoerper, AXAM2 antikoerper, SMT3IP2 antikoerper, Axam antikoerper, SUMO/sentrin specific peptidase 2 antikoerper, SUMO1/sentrin/SMT3 specific peptidase 2 antikoerper, Sumo1/sentrin/SMT3 specific peptidase 2 antikoerper, Senp2 antikoerper, SENP2 antikoerper
    Hintergrund
    SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
    Molekulargewicht
    67855
    Gen-ID
    59343
    NCBI Accession
    NP_067640
    UniProt
    Q9HC62
    Pathways
    Chromatin Binding
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