Drosophila SUMO (AA 37-66) Antikörper

Produktnummer ABIN388088

Produktdetails

Target: Drosophila SUMO

Bindungsspezifität: AA 37-66

Reaktivität: Drosophila melanogaster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Drosophila SUMO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids of Drosophila SUMO.

Klon: RB3488

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen

Maarifi, Hannoun, Geoffroy, El Asmi, Zarrouk, Nisole, Blondel, Chelbi-Alix: "MxA Mediates SUMO-Induced Resistance to Vesicular Stomatitis Virus." in: Journal of virology, Vol. 90, Issue 14, pp. 6598-6610, (2017) (PubMed).

Kearse, Ireland, Prem, Chen, Ware: "RpL22e, but not RpL22e-like-PA, is SUMOylated and localizes to the nucleoplasm of Drosophila meiotic spermatocytes." in: Nucleus (Austin, Tex.), Vol. 4, Issue 3, pp. 241-58, (2013) (PubMed).

Sahota, Grau, Mansilla, Ferrús: "Troponin I and Tropomyosin regulate chromosomal stability and cell polarity." in: Journal of cell science, Vol. 122, Issue Pt 15, pp. 2623-31, (2009) (PubMed).

Antigendetails

Target: Drosophila SUMO

Hintergrund: Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. In the development of Drosophila, SUMO plays a maternal role in anterior-posterior (A/P) polarity and patterning.

Molekulargewicht: 10124

Gen-ID: 33981

UniProt: O97102