Caspase 10 Antikörper (AA 164-192)

Produktnummer ABIN388121

Produktdetails anti-Caspase 10 Antikörper

Target: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Bindungsspezifität: AA 164-192

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CASP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-192 amino acids from the Central region of human CASP10.

Klon: RB18398

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Caspase 10

Target: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Andere Bezeichnung: CASP10 (CASP10 Produkte)

Synonyme: xCaspase-10 antikoerper, alps2 antikoerper, caspace-10 antikoerper, caspase-10 antikoerper, flice2 antikoerper, mch4 antikoerper, xCaspace-10 antikoerper, ALPS2 antikoerper, FLICE2 antikoerper, MCH4 antikoerper, caspase 10 S homeolog antikoerper, caspase 10 antikoerper, caspase-10 antikoerper, casp10.S antikoerper, casp10 antikoerper, CASP10 antikoerper, Casp10 antikoerper, LOC100848685 antikoerper

Hintergrund: CASP10 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in the protein are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.

Molekulargewicht: 58951

Gen-ID: 843

NCBI Accession: NP_001193453, NP_001193471, NP_001221, NP_116756, NP_116758, NP_116759

UniProt: Q92851

Pathways: Apoptose, Caspase Kaskade in der Apoptose