This ABCG2 (BCRP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313~342 amino acids from the center region of human ABCG2.
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This ABCG2 (BCRP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-335 AA from the Central region of human ABCG2 (BCRP).
bcrp antikoerper, ABCG2 antikoerper, ABC15 antikoerper, ABCP antikoerper, BCRP antikoerper, BCRP1 antikoerper, BMDP antikoerper, CD338 antikoerper, CDw338 antikoerper, EST157481 antikoerper, GOUT1 antikoerper, MRX antikoerper, MXR antikoerper, MXR1 antikoerper, UAQTL1 antikoerper, AI428558 antikoerper, Bcrp1 antikoerper, ABCG3 antikoerper, ATP binding cassette subfamily G member 2 antikoerper, ATP binding cassette subfamily G member 2 (Junior blood group) antikoerper, ATP binding cassette subfamily G member 2 (Junior blood group) L homeolog antikoerper, ATP-binding cassette, sub-family G (WHITE), member 2 antikoerper, ATP-binding cassette sub-family G member 2 antikoerper, ABCG2 antikoerper, abcg2 antikoerper, abcg2.L antikoerper, Abcg2 antikoerper, LOC100008640 antikoerper
Hintergrund
ABCG2 is a membrane-associated protein included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Synonyms: ATP-binding cassette sub-family G member 2, Placenta-specific ATP-binding cassette transporter, Breast cancer resistance protein, Mitoxantrone resistance-associated protein, CD338 antigen, CDw338, ABCP, BCRP, BCRP1, MXR