Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This Bmp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 957-986 amino acids from the C-terminal region of human Bmp1.
OI13 antikoerper, PCOLC antikoerper, PCP antikoerper, PCP2 antikoerper, TLD antikoerper, Pcp antikoerper, Tld antikoerper, BMP1 antikoerper, submp antikoerper, tld antikoerper, xtld antikoerper, bmp-1 antikoerper, pcolc antikoerper, xbmp1 antikoerper, tolloid antikoerper, BMP-1 antikoerper, bmp1 antikoerper, bmp1a antikoerper, bone morphogenetic protein 1 antikoerper, Bone morphogenetic protein 1 antikoerper, bone morphogenetic protein 1 S homeolog antikoerper, bone morphogenetic protein 1, like antikoerper, BMP1 antikoerper, Bmp1 antikoerper, bmp1 antikoerper, bmp1.S antikoerper, bmp1l antikoerper
Hintergrund
The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors. BMP1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.