ATG4B Antikörper (AA 258-284)

Produktnummer ABIN388497

Produktdetails anti-ATG4B Antikörper

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Bindungsspezifität: AA 258-284

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B, C, Zf, M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATG4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-284 amino acids from human ATG4B.

Klon: RB11843

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu ATG4B

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Andere Bezeichnung: ATG4B (ATG4B Produkte)

Synonyme: apg4b antikoerper, APG4B antikoerper, AUTL1 antikoerper, 2510009N07Rik antikoerper, AW048066 antikoerper, Apg4b antikoerper, Atg4bl antikoerper, Autl1 antikoerper, Aut2b2 antikoerper, autophagy related 4B cysteine peptidase antikoerper, autophagy-related 4b antikoerper, Peptidase family C54 protein antikoerper, cysteine protease ATG4B antikoerper, ATG4 autophagy related 4 homolog B (S. cerevisiae) antikoerper, autophagy related 4B, cysteine peptidase antikoerper, autophagy related 4B, cysteine peptidase L homeolog antikoerper, ATG4B antikoerper, Atg4b antikoerper, AT3G59950 antikoerper, Tsp_08582 antikoerper, Tsp_11599 antikoerper, atg4b antikoerper, atg4b.L antikoerper

Hintergrund: Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4, a cysteine protease required for autophagy, cleaves the C-terminal part of MAP1LC3 to form the activated molecule LC3-I. LC3-I is subsequently conjugated with phosphatidylethanolamine at the C-terminal glycine to form LC3-II, a marker for autophagy via its capacity to bind to autophagosomes.

Molekulargewicht: 44294

Gen-ID: 23192

NCBI Accession: NP_037457, NP_847896

UniProt: Q9Y4P1

Pathways: Autophagie