Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This LAMP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the N-terminal region of human LAMP1.
LAMP1
Reaktivität: Human
FACS, IHC
Wirt: Maus
Monoclonal
H4A3
Biotin
Applikationshinweise
WB: 1:1000. IHC-P: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Funk, Mrak, Kuret: "Granulovacuolar degeneration (GVD) bodies of Alzheimer's disease (AD) resemble late-stage autophagic organelles." in: Neuropathology and applied neurobiology, Vol. 37, Issue 3, pp. 295-306, (2011) (PubMed).
Kim, Woo, Yoon, Lee, An, Choi, Hwang, Yoon, Lee: "Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation." in: The Journal of biological chemistry, Vol. 286, Issue 15, pp. 12924-32, (2011) (PubMed).
Hnasko, Lin, McGarvey, Stanker: "A rapid method to improve protein detection by indirect ELISA." in: Biochemical and biophysical research communications, Vol. 410, Issue 4, pp. 726-31, (2011) (PubMed).
Byun, Yoon, An, Park, Kang, Kim, Lee: "The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras." in: Carcinogenesis, Vol. 30, Issue 11, pp. 1880-8, (2009) (PubMed).
Target
LAMP1
(Lysosomal-Associated Membrane Protein 1 (LAMP1))
LAMP1 is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis.