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PIK3C3 Antikörper (AA 405-430)

PIK3C3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB11903 unconjugated
Produktnummer ABIN388597
  • Target Alle PIK3C3 Antikörper anzeigen
    PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))
    Bindungsspezifität
    • 22
    • 22
    • 19
    • 16
    • 13
    • 12
    • 12
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 405-430
    Reaktivität
    • 185
    • 59
    • 53
    • 2
    • 1
    Human
    Wirt
    • 183
    • 2
    Kaninchen
    Klonalität
    • 176
    • 9
    Polyklonal
    Konjugat
    • 51
    • 20
    • 19
    • 19
    • 15
    • 15
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser PIK3C3 Antikörper ist unkonjugiert
    Applikation
    • 146
    • 107
    • 82
    • 40
    • 39
    • 23
    • 22
    • 17
    • 16
    • 15
    • 10
    • 9
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PI3KC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-430 amino acids from human PI3KC3.
    Klon
    RB11903
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PIK3C3 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))
    Andere Bezeichnung
    PI3KC3 (PIK3C3 Produkte)
    Synonyme
    im:7147158 antikoerper, wu:fc13g06 antikoerper, wu:fz51e12 antikoerper, zgc:112016 antikoerper, zgc:113009 antikoerper, VPS34 antikoerper, hVps34 antikoerper, 5330434F23Rik antikoerper, Vps34 antikoerper, phosphatidylinositol 3-kinase catalytic subunit type 3 antikoerper, phosphatidylinositol 3-kinase catalytic subunit type 3 L homeolog antikoerper, phosphatidylinositol 3-kinase, catalytic subunit type 3 antikoerper, PIK3C3 antikoerper, pik3c3.L antikoerper, pik3c3 antikoerper, Pik3c3 antikoerper
    Hintergrund
    PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to 1-phosphatidyl-1D-myo-inositol 3-phosphate. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). The regulation of the Beclin 1-PI3KC3 complex lipid kinase activity is a critical element in the autophagy signaling pathway.
    Molekulargewicht
    101549
    Gen-ID
    5289
    NCBI Accession
    NP_002638
    UniProt
    Q8NEB9
    Pathways
    AMPK Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Toll-Like Receptors Cascades, Autophagie
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