NMD3 Antikörper (C-Term)

Produktnummer ABIN388665

Produktdetails anti-NMD3 Antikörper

Target: NMD3 (60S Ribosomal Export Protein NMD3 (NMD3))

Bindungsspezifität: AA 410-440, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This NMD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-440 amino acids from the C-terminal region of human NMD3.

Klon: RB9708

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu NMD3

Target: NMD3 (60S Ribosomal Export Protein NMD3 (NMD3))

Andere Bezeichnung: NMD3 (NMD3 Produkte)

Synonyme: RGD1308468 antikoerper, C87860 antikoerper, nmd3l antikoerper, zgc:113103 antikoerper, NMD3 ribosome export adaptor antikoerper, NMD3 homolog (S. cerevisiae) antikoerper, NMD3 ribosome export adaptor L homeolog antikoerper, Nmd3 antikoerper, NMD3 antikoerper, nmd3 antikoerper, nmd3.L antikoerper

Hintergrund: It has been suggested that NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit but is not a ribosomal protein. A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. The NMD3 protein sequence does not contain readily recognizable motifs of known function. However, NMD3 orthologues display an amino-terminal domain containing four repeats of Cx2C, reminiscent of zinc-binding proteins, implicated in nucleic acid binding or protein oligomerization.

Molekulargewicht: 57603

Gen-ID: 51068

NCBI Accession: NP_057022

UniProt: Q96D46