EIF4E Antikörper (N-Term)

Produktnummer ABIN388675

Produktdetails anti-EIF4E Antikörper

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Bindungsspezifität: AA 32-61, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF4E Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Zf, B, M, Rb, Rat, X

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This EIF4E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human EIF4E.

Klon: RB11725

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu EIF4E

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Andere Bezeichnung: EIF4E (EIF4E Produkte)

Synonyme: AUTS19 antikoerper, CBP antikoerper, EIF4E1 antikoerper, EIF4EL1 antikoerper, EIF4F antikoerper, eif4e-1 antikoerper, zgc:86680 antikoerper, EG668879 antikoerper, Eif4e-ps antikoerper, If4e antikoerper, eIF-4E antikoerper, 0260/09 antikoerper, 0587/11 antikoerper, 0589/11 antikoerper, 0919/12 antikoerper, 1004/13 antikoerper, 2 antikoerper, 7238 antikoerper, CG4035 antikoerper, CT13384 antikoerper, CT39424 antikoerper, CT39426 antikoerper, D-eIF4E antikoerper, Dmel\\CG4035 antikoerper, Eif4E antikoerper, Eif4e antikoerper, IF4E antikoerper, dEif4e antikoerper, deIF-4E antikoerper, deIF4E antikoerper, eIF 4E antikoerper, eIF-4E1 antikoerper, eIF-4E2 antikoerper, eIF-4EII antikoerper, eIF-4e antikoerper, eIF4E antikoerper, eIF4E-1 antikoerper, eIF4E-1/2 antikoerper, eIF4E-2 antikoerper, eIF4E1 antikoerper, eIF4EI antikoerper, eIF4e antikoerper, eif-4E antikoerper, eif-4e antikoerper, eif4e antikoerper, l(3)07238 antikoerper, l(3)67Af antikoerper, l(3)S025007 antikoerper, l(3)S026009 antikoerper, l(3)S058711 antikoerper, l(3)S091912 antikoerper, cbp antikoerper, eif4f antikoerper, eif4e1 antikoerper, eif4el1 antikoerper, EIF-4E antikoerper, zgc:101581 antikoerper, eukaryotic translation initiation factor 4E antikoerper, eukaryotic translation initiation factor 4ea antikoerper, Eukaryotic initiation factor 4E antikoerper, eucaryotic initiation factor 6 antikoerper, eukaryotic translation initiation factor 4E L homeolog antikoerper, eukaryotic translation initiation factor 4E family member 1B S homeolog antikoerper, translation initiation factor eIF4E antikoerper, eukaryotic translation initiation factor 4eb antikoerper, EIF4E antikoerper, eif4ea antikoerper, Eif4e antikoerper, eIF-4E antikoerper, eif6 antikoerper, eif4e antikoerper, eif4e.L antikoerper, eif4e1b.S antikoerper, LOC100533326 antikoerper, eif4eb antikoerper

Hintergrund: EIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners. The interaction with EIF4ENIF1 mediates the import into the nucleus. Nonphosphorylated EIF4EBP1, EIF4EBP2 and EIF4EBP3 compete with EIF4G1/EIF4G3 to interact with EIF4E, insulin stimulated MAP-kinase (MAPK1 and MAPK3) phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initiation of translation. Rapamycin can attenuate insulin stimulation, mediated by FKBPs. this gene also interacts mutually exclusive with EIF4A1 and EIF4A2.

Molekulargewicht: 25097

Gen-ID: 1977

NCBI Accession: NP_001124150, NP_001124151, NP_001959

UniProt: P06730

Pathways: BCR Signaling