This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This LEO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the N-terminal region of human LEO1.
LEO1 antikoerper, RDL antikoerper, Gm185 antikoerper, zgc:77374 antikoerper, LEO1 homolog, Paf1/RNA polymerase II complex component antikoerper, Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) antikoerper, RNA polymerase-associated protein LEO1 antikoerper, LEO1 homolog, Paf1/RNA polymerase II complex component S homeolog antikoerper, Leo1, Paf1/RNA polymerase II complex component antikoerper, LEO1 antikoerper, leo1 antikoerper, LOC100466503 antikoerper, leo1.S antikoerper, Leo1 antikoerper, LOC415420 antikoerper, LOC478310 antikoerper
Hintergrund
The PAF1 complex is a multifunctional complex. The PAF1 complex interacts with POLR2A. It may be involved in both initiation and elongation, histone methylation and RNA processing. Overexpression of LEO1 induces cell growth arrest and premature senescence of fibroblasts.