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c-MYC Antikörper (AA 351-380)
MYC
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB11189
unconjugated
Produktdetails anti-c-MYC Antikörper
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Target
Alle c-MYC (MYC) Antikörper anzeigen
c-MYC (MYC)
(Myc Proto-Oncogene protein (MYC))
Bindungsspezifität
Alle Epitope für c-MYC Antikörper
AA 351-380
Reaktivität
Alle Reaktivitäten für c-MYC Antikörper
Human
Wirt
Alle Wirte für c-MYC Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für c-MYC Antikörper
Polyklonal
Konjugat
Alle Konjugate für c-MYC Antikörper
Dieser c-MYC Antikörper ist unkonjugiert
Applikation
Alle Applikationen für c-MYC Antikörper
Western Blotting (WB)
Homologie
B, M, Rat, Sh
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MYC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-380 amino acids from human MYC.
Klon
RB11189
Isotyp
Ig Fraction
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB: 1:1000. WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Details zu c-MYC
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Target
c-MYC (MYC)
(Myc Proto-Oncogene protein (MYC))
Andere Bezeichnung
Myc Proto-Oncogene protein (MYC Produkte )
Synonyme
MRTL antikoerper, MYCC antikoerper, bHLHe39 antikoerper, c-Myc antikoerper, CMYC antikoerper, c-myc antikoerper, C-MYC antikoerper, LOC100136746 antikoerper, ARC antikoerper, B430311C09Rik antikoerper, MYC antikoerper, NOP antikoerper, Nop30 antikoerper, RNCMYC antikoerper, mMyc antikoerper, AU016757 antikoerper, Myc2 antikoerper, Niard antikoerper, Nird antikoerper, cmyc antikoerper, zc-myc antikoerper, c-myc II antikoerper, myc-B antikoerper, myc2 antikoerper, myc1 antikoerper, CMyc antikoerper, zgc:55680 antikoerper, CG10798 antikoerper, D-Myc antikoerper, DM antikoerper, DMYc antikoerper, Dm antikoerper, Dmel\CG10798 antikoerper, Dmyc antikoerper, EG:BACN5I9.1 antikoerper, anon-WO03040301.171 antikoerper, bHLHe57 antikoerper, c-MYC antikoerper, d-myc antikoerper, dMYC antikoerper, dMyc antikoerper, dMyc1 antikoerper, da antikoerper, dm antikoerper, dm/dMyc antikoerper, dm/myc antikoerper, dmyc antikoerper, dmyc1 antikoerper, l(1)G0139 antikoerper, l(1)G0354 antikoerper, l(1)G0359 antikoerper, myc antikoerper, MYC proto-oncogene, bHLH transcription factor antikoerper, v-myc myelocytomatosis viral oncogene homolog antikoerper, nucleolar protein 3 (apoptosis repressor with CARD domain) antikoerper, myelocytomatosis oncogene antikoerper, MYC proto-oncogene, bHLH transcription factor a antikoerper, MYC proto-oncogene, bHLH transcription factor L homeolog antikoerper, MYC proto-oncogene, bHLH transcription factor S homeolog antikoerper, v-myc myelocytomatosis viral oncogene homolog (avian) antikoerper, MYC proto-oncogene, bHLH transcription factor b antikoerper, CG10798 gene product from transcript CG10798-RB antikoerper, MYC antikoerper, LOC100136746 antikoerper, Nol3 antikoerper, Myc antikoerper, myca antikoerper, myc.L antikoerper, myc.S antikoerper, mycb antikoerper
Hintergrund
MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of the gene encoding MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Molekulargewicht
48804
Gen-ID
4609
NCBI Accession
NP_002458
UniProt
P01106
Pathways
p53 Signalweg , Zellzyklus , Sensory Perception of Sound , Transition Metal Ion Homeostasis , Mitotic G1-G1/S Phases , Positive Regulation of Endopeptidase Activity , Regulation of Carbohydrate Metabolic Process , Positive Regulation of Response to DNA Damage Stimulus , Warburg Effekt
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