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ASCL1 Antikörper (C-Term)

ASCL1 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB02899 unconjugated
Produktnummer ABIN388761
  • Target Alle ASCL1 Antikörper anzeigen
    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
    Bindungsspezifität
    • 15
    • 14
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 166-196, C-Term
    Reaktivität
    • 83
    • 48
    • 32
    • 9
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Human, Maus
    Wirt
    • 83
    • 5
    • 3
    Kaninchen
    Klonalität
    • 86
    • 5
    Polyklonal
    Konjugat
    • 38
    • 10
    • 8
    • 8
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ASCL1 Antikörper ist unkonjugiert
    Applikation
    • 73
    • 54
    • 23
    • 13
    • 13
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Homologie
    Rat
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This ASCL1 (Achaete-scute homolog 1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-196 amino acids from the C-terminal region of human ASCL1 (Achaete-scute homolog 1).
    Klon
    RB02899
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ASCL1 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze-thaw cycles.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    Haltbarkeit
    6 months
  • Target
    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
    Andere Bezeichnung
    ASCL1 (Achaete-scute homolog 1) (ASCL1 Produkte)
    Synonyme
    ASH1 antikoerper, HASH1 antikoerper, MASH1 antikoerper, bHLHa46 antikoerper, AI225900 antikoerper, Mash1 antikoerper, ASCL1 antikoerper, Zash-1a antikoerper, ash antikoerper, asha antikoerper, id:ibd5085 antikoerper, im:7138587 antikoerper, si:dkey-264k15.2 antikoerper, zash1a antikoerper, zasha antikoerper, Xash1 antikoerper, ascl1-A antikoerper, Zash-1b antikoerper, ashb antikoerper, zashb antikoerper, achaete-scute family bHLH transcription factor 1 antikoerper, achaete-scute family bHLH transcription factor 1a antikoerper, achaete-scute family bHLH transcription factor 1 L homeolog antikoerper, achaete-scute complex homolog 1 antikoerper, achaete-scute family bHLH transcription factor 1b antikoerper, ASCL1 antikoerper, Ascl1 antikoerper, ascl1a antikoerper, ascl1.L antikoerper, LOC100220505 antikoerper, ascl1b antikoerper
    Hintergrund
    ACSL1, alternatively titled Hash1 or Mash1, is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. ACSL1 plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. The protein is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers. The presence of a CAG repeat in the gene suggests it may also play a role in tumor formation.
    Molekulargewicht
    25454
    Gen-ID
    429
    NCBI Accession
    NP_004307
    UniProt
    P50553
    Pathways
    Dopaminergic Neurogenesis
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