USP15 Antikörper (N-Term)

Produktnummer ABIN388904

Produktdetails anti-USP15 Antikörper

Target: USP15 (Ubiquitin Specific Peptidase 15 (USP15))

Bindungsspezifität: AA 151-180, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This USP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the N-terminal region of human USP15.

Klon: RB4337

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:25. WB: 1:1000. WB: 1:1000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:2500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu USP15

Target: USP15 (Ubiquitin Specific Peptidase 15 (USP15))

Andere Bezeichnung: USP15 (USP15 Produkte)

Synonyme: USP15 antikoerper, UNP antikoerper, UNPH-2 antikoerper, UNPH4 antikoerper, 4921514G19Rik antikoerper, AI327321 antikoerper, E430033I05Rik antikoerper, Gcap18 antikoerper, mKIAA0529 antikoerper, Ubp109 antikoerper, ubiquitin specific peptidase 15 antikoerper, universal stress protein UspA antikoerper, ubiquitin carboxyl-terminal hydrolase 15 antikoerper, USP15 antikoerper, RR_RS05795 antikoerper, LOC100090554 antikoerper, usp15 antikoerper, Usp15 antikoerper

Hintergrund: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Molekulargewicht: 112419

Gen-ID: 9958

NCBI Accession: NP_001239007, NP_001239008, NP_006304

UniProt: Q9Y4E8