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USP28 Antikörper (N-Term)

USP28 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB4435 unconjugated
Produktnummer ABIN388921
  • Target Alle USP28 Antikörper anzeigen
    USP28 (Ubiquitin Specific Peptidase 28 (USP28))
    Bindungsspezifität
    • 15
    • 7
    • 7
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 111-141, N-Term
    Reaktivität
    • 40
    • 17
    • 2
    • 1
    • 1
    Human
    Wirt
    • 52
    • 2
    • 1
    Kaninchen
    Klonalität
    • 55
    Polyklonal
    Konjugat
    • 17
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser USP28 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 20
    • 13
    • 13
    • 13
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This USP28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-141 amino acids from the N-terminal region of human USP28.
    Klon
    RB4435
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product USP28 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    USP28 (Ubiquitin Specific Peptidase 28 (USP28))
    Andere Bezeichnung
    USP28 (USP28 Produkte)
    Synonyme
    im:7138195 antikoerper, USP28 antikoerper, 9830148O20Rik antikoerper, AU022237 antikoerper, mKIAA1515 antikoerper, ubiquitin specific peptidase 28 antikoerper, USP28 antikoerper, usp28 antikoerper, Usp28 antikoerper
    Hintergrund
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    Molekulargewicht
    122491
    Gen-ID
    57646
    NCBI Accession
    NP_065937
    UniProt
    Q96RU2
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