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Ubiquilin 1 Antikörper (N-Term)

UBQLN1 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB4615 unconjugated
Produktnummer ABIN388971
  • Target Alle Ubiquilin 1 (UBQLN1) Antikörper anzeigen
    Ubiquilin 1 (UBQLN1)
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 19-49, N-Term
    Reaktivität
    • 54
    • 26
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 47
    • 6
    • 2
    Kaninchen
    Klonalität
    • 50
    • 5
    Polyklonal
    Konjugat
    • 30
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Ubiquilin 1 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 35
    • 21
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Rat
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This Ubiquilin1 (PLIC1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-49 amino acids from the N-terminal region of human Ubiquilin1 (PLIC1).
    Klon
    RB4615
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product UBQLN1 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Sick, Boukhari, Deramaudt, Rondé, Bucher, André, Gies, Takeda: "Activation of CD47 receptors causes proliferation of human astrocytoma but not normal astrocytes via an Akt-dependent pathway." in: Glia, Vol. 59, Issue 2, pp. 308-19, (2010) (PubMed).

  • Target
    Ubiquilin 1 (UBQLN1)
    Andere Bezeichnung
    Ubiquilin1 (PLIC1) (UBQLN1 Produkte)
    Hintergrund
    PLIC1 is an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease.
    Molekulargewicht
    62519
    Gen-ID
    29979
    NCBI Accession
    NP_038466, NP_444295
    UniProt
    Q9UMX0
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