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ARL3 Antikörper (C-Term)

ARL3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB4911-4912 unconjugated
Produktnummer ABIN389001
  • Target Alle ARL3 Antikörper anzeigen
    ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 1
    AA 144-173, C-Term
    Reaktivität
    • 51
    • 12
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 6
    Kaninchen
    Klonalität
    • 47
    • 4
    Polyklonal
    Konjugat
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ARL3 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 18
    • 13
    • 13
    • 10
    • 5
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This ARL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-173 amino acids from the C-terminal region of human ARL3.
    Klon
    RB4911-4912
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))
    Andere Bezeichnung
    ARL3 (ARL3 Produkte)
    Synonyme
    ARFL3 antikoerper, si:ch211-208d15.4 antikoerper, wu:fj22g05 antikoerper, arfl3 antikoerper, arl3 antikoerper, ADP ribosylation factor like GTPase 3 antikoerper, ADP-ribosylation factor-like 3 antikoerper, ADP ribosylation factor like GTPase 3 S homeolog antikoerper, ADP-ribosylation factor-like protein 3 antikoerper, ARL3 antikoerper, arl3 antikoerper, Arl3 antikoerper, arl3.1.S antikoerper, arl-3 antikoerper
    Hintergrund
    ADP-ribosylation factors (ARFs) are low molecular weight GTP-binding proteins belonging to the RAS superfamily. The predicted 182-amino acid ARL3 (ADP-ribosylation like factor) protein shares 97 % amino acid identity with rat ARLl3 and 43 % identity with human ARF1. Like the ARFs, ARL3 has a glycine at position 2, the site of N myristoylation, and lacks cysteine residues near the C terminus, which are found in other members of the RAS family. Northern blot analysis detected a 1-kb ARL3 transcript in all tissues tested, with highest expression in heart and lung, and lower expression in brain, liver, kidney, ovary, and testis. A 5.5-kb transcript was also detected in most tissues, with highest expression in brain. Immunoblot analysis detected ARL3 in human tumor cell lines but not in normal rodent cells. Although ARL3 binds GTP, it is devoid of activity in the cholera toxin-dependent ADP-ribosylation of Gs, and is therefore classified as an ARF-like protein.
    Molekulargewicht
    20456
    Gen-ID
    403
    NCBI Accession
    NP_004302
    UniProt
    P36405
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