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Doublecortin Antikörper (AA 107-137)

DCX Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB15193 unconjugated
Produktnummer ABIN389254
  • Target Alle Doublecortin (DCX) Antikörper anzeigen
    Doublecortin (DCX)
    Bindungsspezifität
    • 7
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 107-137
    Reaktivität
    • 109
    • 70
    • 65
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 98
    • 13
    • 2
    • 1
    Kaninchen
    Klonalität
    • 94
    • 20
    Polyklonal
    Konjugat
    • 61
    • 9
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Doublecortin Antikörper ist unkonjugiert
    Applikation
    • 73
    • 43
    • 31
    • 13
    • 12
    • 10
    • 9
    • 8
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This DCX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-137 amino acids from human DCX.
    Klon
    RB15193
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product DCX Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    Doublecortin (DCX)
    Andere Bezeichnung
    DCX (DCX Produkte)
    Synonyme
    DCX antikoerper, DBCN antikoerper, DC antikoerper, LISX antikoerper, SCLH antikoerper, XLIS antikoerper, Dbct antikoerper, 18C15.5 antikoerper, doublecortin antikoerper, DCX antikoerper, Dcx antikoerper
    Hintergrund
    In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.
    Molekulargewicht
    40574
    Gen-ID
    1641
    NCBI Accession
    NP_000546, NP_835364, NP_835365, NP_835366
    UniProt
    O43602
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