SNURF Antikörper (AA 4-32)

Produktnummer ABIN389318

Produktdetails anti-SNURF Antikörper

Target: SNURF (SNRPN Upstream Reading Frame (SNURF))

Bindungsspezifität: AA 4-32

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNURF Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Homologie: B, M, Rb

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SNURF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the Central region of human SNURF.

Klon: RB17346

Isotyp: Ig Fraction

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu SNURF

Target: SNURF (SNRPN Upstream Reading Frame (SNURF))

Andere Bezeichnung: SNURF (SNURF Produkte)

Synonyme: 2410045I01Rik antikoerper, Snrpn antikoerper, SNRPN upstream reading frame antikoerper, small nuclear ribonucleoprotein polypeptide N antikoerper, SNURF antikoerper, SNRPN antikoerper, Snurf antikoerper

Hintergrund: SNURF is a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame of its gene is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known.

Molekulargewicht: 8412

Gen-ID: 8926

NCBI Accession: NP_005669, NP_073715

UniProt: Q9Y675