PFDN6 Antikörper (N-Term)
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- Target Alle PFDN6 Antikörper anzeigen
- PFDN6 (Prefoldin Subunit 6 (PFDN6))
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Bindungsspezifität
- AA 6-34, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PFDN6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Homologie
- B, M
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This PFDN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human PFDN6.
- Klon
- RB17559
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product PFDN6 Primärantikörper
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation." in: The Journal of biological chemistry, Vol. 288, Issue 27, pp. 19958-72, (2013) (PubMed).
: "Prefoldin plays a role as a clearance factor in preventing proteasome inhibitor-induced protein aggregation." in: The Journal of biological chemistry, Vol. 288, Issue 39, pp. 27764-76, (2013) (PubMed).
: "Prefoldin subunits are protected from ubiquitin-proteasome system-mediated degradation by forming complex with other constituent subunits." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19191-203, (2011) (PubMed).
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Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation." in: The Journal of biological chemistry, Vol. 288, Issue 27, pp. 19958-72, (2013) (PubMed).
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- Target
- PFDN6 (Prefoldin Subunit 6 (PFDN6))
- Andere Bezeichnung
- PFDN6 (PFDN6 Produkte)
- Synonyme
- hke2 antikoerper, ke-2 antikoerper, pfd6 antikoerper, h2-ke2 antikoerper, pfdn6a antikoerper, 23.m05913 antikoerper, H-2Ke2 antikoerper, Ke-2 antikoerper, Pfdn6 antikoerper, H2-KE2 antikoerper, HKE2 antikoerper, KE-2 antikoerper, PFD6 antikoerper, zgc:66282 antikoerper, pfdn6 antikoerper, pfdn6b antikoerper, Ke2 antikoerper, prefoldin subunit 6 S homeolog antikoerper, prefoldin subunit 6 (predicted) antikoerper, prefoldin subunit 6 antikoerper, prefoldin subunit 6 L homeolog antikoerper, pfdn6.S antikoerper, SPAC3A11.13 antikoerper, BBOV_IV004800 antikoerper, AOR_1_2254174 antikoerper, CMU_042830 antikoerper, pfdn6 antikoerper, Pfdn6 antikoerper, PFDN6 antikoerper, pfdn6.L antikoerper
- Hintergrund
- PFDN6 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. This protein also binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
- Molekulargewicht
- 14583
- Gen-ID
- 10471
- NCBI Accession
- NP_001172110, NP_001252524, NP_001252525, NP_055075
- UniProt
- O15212
- Pathways
- Unfolded Protein Response
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