APRT Antikörper (N-Term)

Produktnummer ABIN389426

Produktdetails anti-APRT Antikörper

Target: APRT (Adenine Phosphoribosyltransferase (APRT))

Bindungsspezifität: AA 12-40, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APRT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This APRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human APRT.

Klon: RB20509

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-APRT Antikörper (ABIN389426)

Valaperta, Rizzo, Lombardi, Verdelli, Piccoli, Ghiroldi, Creo, Colombo, Valisi, Margiotta, Panella, Costa: "Adenine phosphoribosyltransferase (APRT) deficiency: identification of a novel nonsense mutation." in: BMC nephrology, Vol. 15, pp. 102, (2014) (PubMed).

Details zu APRT

Target: APRT (Adenine Phosphoribosyltransferase (APRT))

Andere Bezeichnung: APRT (APRT Produkte)

Synonyme: Tb07.43M14.200 antikoerper, Tb07.43M14.180 antikoerper, C85684 antikoerper, AMP antikoerper, APRTD antikoerper, adenine phosphoribosyltransferase antikoerper, adenine phosphoribosyl transferase antikoerper, CND05020 antikoerper, Tb927.7.1790 antikoerper, Tb927.7.1780 antikoerper, Arnit_0941 antikoerper, Saut_1231 antikoerper, Fbal_1180 antikoerper, PH_RS07970 antikoerper, PF_RS08760 antikoerper, PAB_RS02560 antikoerper, Aprt antikoerper, APRT antikoerper

Hintergrund: A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.

Molekulargewicht: 19608

Gen-ID: 353

NCBI Accession: NP_000476, NP_001025189

UniProt: P07741

Pathways: Ribonucleoside Biosynthetic Process