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APRT Antikörper (C-Term)

APRT Reaktivität: Human, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal RB20510 unconjugated
Produktnummer ABIN389427
  • Target Alle APRT Antikörper anzeigen
    APRT (Adenine Phosphoribosyltransferase (APRT))
    Bindungsspezifität
    • 13
    • 8
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 143-170, C-Term
    Reaktivität
    • 50
    • 5
    • 3
    • 2
    • 1
    • 1
    Human, Ratte
    Wirt
    • 47
    • 3
    Kaninchen
    Klonalität
    • 49
    • 1
    Polyklonal
    Konjugat
    • 29
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser APRT Antikörper ist unkonjugiert
    Applikation
    • 37
    • 20
    • 18
    • 9
    • 8
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This APRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-170 amino acids from the C-terminal region of human APRT.
    Klon
    RB20510
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product APRT Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Valaperta, Rizzo, Lombardi, Verdelli, Piccoli, Ghiroldi, Creo, Colombo, Valisi, Margiotta, Panella, Costa: "Adenine phosphoribosyltransferase (APRT) deficiency: identification of a novel nonsense mutation." in: BMC nephrology, Vol. 15, pp. 102, (2014) (PubMed).

  • Target
    APRT (Adenine Phosphoribosyltransferase (APRT))
    Andere Bezeichnung
    APRT (APRT Produkte)
    Hintergrund
    A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.
    Molekulargewicht
    19608
    Gen-ID
    353
    NCBI Accession
    NP_000476, NP_001025189
    UniProt
    P07741
    Pathways
    Ribonucleoside Biosynthetic Process
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