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VEGFR2/CD309 Antikörper (pTyr996)

Name: VEGFR2/CD309 Antikörper (pTyr996)
SKU: ABIN389564
Price: 445.5 EUR
Availability: InStock

VEGFR2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB2667 unconjugated

Anti-Phospho-KDR/FLK1- Pab (ABIN389564 and ABIN2839596) is used in Western blot to detect Phospho-KDR/FLK1- in HMVEC cell line lysate. (VEGFR2/CD309 Antikörper (pTyr996))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (VEGFR2/CD309 Antikörper (pTyr996))

IHC (p)

2 Abbildungen

(1 reference)

Produktnummer ABIN389564

Datenblatt (PDF)

Target Alle VEGFR2/CD309 (VEGFR2) Antikörper anzeigen

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
Bindungsspezifität
42

36

27

24

20

16

16

15

15

10

10

8

8

6

6

6

5

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr996
Reaktivität
318

207

145

17

9

5

3

3

3

3

1

1

1

1

1

1

1

1

1

1
Human
Wirt
304

57

23

1

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
297

90
Polyklonal
Konjugat
164

35

20

15

13

12

9

9

7

7

7

7

6

6

6

6

6

6

6

6

6

6

6

3

2

2

2

1

1

1

1

1

1

1
Dieser VEGFR2/CD309 Antikörper ist unkonjugiert
Applikation
225

136

100

94

64

26

26

24

19

14

13

12

9

8

7

4

3

2

2

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This KDR/FLK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y996 of human KDR/FLK1.

Klon

RB2667

Isotyp

Ig Fraction

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Applikationshinweise

WB: 1:1000. IHC-P: 1:50~100

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Wittko, Schänzer, Kuzmichev, Schneider, Shibuya, Raab, Plate: "VEGFR-1 regulates adult olfactory bulb neurogenesis and migration of neural progenitors in the rostral migratory stream in vivo." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 27, pp. 8704-14, (2009) (PubMed).
Target

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Andere Bezeichnung

KDR/FLK1 (VEGFR2 Produkte)

Synonyme

CD309 antikoerper, FLK1 antikoerper, VEGFR antikoerper, VEGFR2 antikoerper, 6130401C07 antikoerper, Flk-1 antikoerper, Flk1 antikoerper, Krd-1 antikoerper, Ly73 antikoerper, VEGFR-2 antikoerper, sVEGFR-2 antikoerper, Vegfr-2 antikoerper, FLK-1 antikoerper, flk-1 antikoerper, vegfr-2 antikoerper, KDR antikoerper, FLK/KDR antikoerper, flk1 antikoerper, flk1b antikoerper, kdrb antikoerper, si:busm1-205d10.1 antikoerper, si:ch211-254j6.1 antikoerper, si:ch211-278f21.4 antikoerper, wu:fc31a09 antikoerper, fk52c05 antikoerper, flk antikoerper, kdr antikoerper, kdra antikoerper, vegfr2 antikoerper, vegfr4 antikoerper, vegr2 antikoerper, wu:fk52c05 antikoerper, kinase insert domain receptor antikoerper, kinase insert domain protein receptor antikoerper, vascular endothelial growth factor receptor kdr-like antikoerper, kinase insert domain receptor (a type III receptor tyrosine kinase) antikoerper, kinase insert domain receptor like antikoerper, KDR antikoerper, Kdr antikoerper, LOC100136647 antikoerper, kdr antikoerper, kdrl antikoerper

Hintergrund

KDR (FLK1) is a receptor for VEGF or VEGFC. This protein has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.

Molekulargewicht

151527

Gen-ID

3791

NCBI Accession

NP_002244

UniProt

P35968

Pathways

RTK Signalweg, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling