Dieser MAPKAP Kinase 2 Antikörper ist unkonjugiert
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)
Homologie
M, Rb
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MAPKAPK2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S272 of human MAPKAPK2.
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Hintergrund
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.