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MEK1 Antikörper (pSer218, pSer222)
MAP2K1
Reaktivität: Human
WB, IHC (p), DB
Wirt: Kaninchen
Polyclonal
RB05985
unconjugated
Produktnummer ABIN2839607
Produktdetails anti-MEK1 Antikörper
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Target
Alle MEK1 (MAP2K1) Antikörper anzeigen
MEK1 (MAP2K1)
(Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
Bindungsspezifität
Alle Epitope für MEK1 Antikörper
pSer218, pSer222
Reaktivität
Alle Reaktivitäten für MEK1 Antikörper
Human
Wirt
Alle Wirte für MEK1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für MEK1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für MEK1 Antikörper
Dieser MEK1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für MEK1 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)
Homologie
D, E, Ha, M, Rb, Rat, X, C
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MEK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S218/222 of human MEK1.
Klon
RB05985
Isotyp
Ig Fraction
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Discover our top product MAP2K1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB: 1:500. IHC-P: 1:50~100. DB: 1:500
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Details zu MEK1
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Target
MEK1 (MAP2K1)
(Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
Andere Bezeichnung
MEK1 (MAP2K1 Produkte )
Synonyme
Mek1 antikoerper, CFC3 antikoerper, MAPKK1 antikoerper, MEK1 antikoerper, MKK1 antikoerper, PRKMK1 antikoerper, MEKK1 antikoerper, Prkmk1 antikoerper, mek-2 antikoerper, si:ch211-242m18.2 antikoerper, wu:fj56a12 antikoerper, wu:fj61b01 antikoerper, zgc:56557 antikoerper, ATMEK1 antikoerper, F20B18.180 antikoerper, F20B18_180 antikoerper, MAP kinase/ ERK kinase 1 antikoerper, MITOGEN ACTIVATED PROTEIN KINASE KINASE antikoerper, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 antikoerper, NMAPKK antikoerper, MEK antikoerper, mitogen activated protein kinase kinase 1 antikoerper, mitogen-activated protein kinase kinase 1 antikoerper, mitogen-activated protein kinase kinase 1 L homeolog antikoerper, MAP kinase/ ERK kinase 1 antikoerper, Map2k1 antikoerper, MAP2K1 antikoerper, map2k1.L antikoerper, map2k1 antikoerper, MEK1 antikoerper
Hintergrund
MEK1is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
Molekulargewicht
43439
Gen-ID
5604
NCBI Accession
NP_002746
UniProt
Q02750
Pathways
MAPK Signalweg , RTK Signalweg , Interferon-gamma Pathway , Fc-epsilon Rezeptor Signalübertragung , Neurotrophin Signalübertragung , Activation of Innate immune Response , Toll-Like Receptors Cascades , Autophagie , Signaling of Hepatocyte Growth Factor Receptor , BCR Signaling
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