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SMAD4 Antikörper (pThr277)

SMAD4 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB07971 unconjugated
Produktnummer ABIN389658
  • Target Alle SMAD4 Antikörper anzeigen
    SMAD4 (SMAD Family Member 4 (SMAD4))
    Bindungsspezifität
    • 12
    • 11
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr277
    Reaktivität
    • 86
    • 38
    • 35
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 75
    • 11
    • 1
    Kaninchen
    Klonalität
    • 61
    • 26
    Polyklonal
    Konjugat
    • 53
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SMAD4 Antikörper ist unkonjugiert
    Applikation
    • 60
    • 36
    • 32
    • 23
    • 21
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SMAD4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4.
    Klon
    RB07971
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SMAD4 Primärantikörper
  • Applikationshinweise
    WB: 1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Arjunan, Gnanaprakasam, Ananth, Romej, Rajalakshmi, Prasad, Martin, Gurusamy, Thangaraju, Bhutia, Ganapathy: "Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis." in: Investigative ophthalmology & visual science, Vol. 57, Issue 4, pp. 1612-9, (2016) (PubMed).

  • Target
    SMAD4 (SMAD Family Member 4 (SMAD4))
    Andere Bezeichnung
    SMAD4 (SMAD4 Produkte)
    Hintergrund
    Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
    Molekulargewicht
    60439
    Gen-ID
    4089
    NCBI Accession
    NP_005350
    UniProt
    Q13485
    Pathways
    Zellzyklus, Chromatin Binding, Autophagie
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