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Crk Antikörper (pSer41)
CRK
Reaktivität: Human
DB
Wirt: Kaninchen
Polyclonal
RB17175
unconjugated
Produktnummer ABIN2837929
Produktdetails anti-Crk Antikörper
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Target
Alle Crk (CRK) Antikörper anzeigen
Crk (CRK)
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
Bindungsspezifität
Alle Epitope für Crk Antikörper
pSer41
Reaktivität
Alle Reaktivitäten für Crk Antikörper
Human
Wirt
Alle Wirte für Crk Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für Crk Antikörper
Polyklonal
Konjugat
Alle Konjugate für Crk Antikörper
Dieser Crk Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Crk Antikörper
Dot Blot (DB)
Homologie
M, Rat
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CRK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S41 of human CRK.
Klon
RB17175
Isotyp
Ig Fraction
Top Product
Discover our top product CRK Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
DB: 1:500
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Details zu Crk
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Target
Crk (CRK)
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
Andere Bezeichnung
CRK (CRK Produkte )
Synonyme
CG1587 antikoerper, CRK antikoerper, D-CRK antikoerper, D-Crk antikoerper, DCrk antikoerper, Dcrk antikoerper, Dmel\\CG1587 antikoerper, crk antikoerper, dCRK antikoerper, dCrk antikoerper, fb34h10 antikoerper, fc05a01 antikoerper, fi19g05 antikoerper, wu:fb34h10 antikoerper, wu:fc05a01 antikoerper, wu:fc54a04 antikoerper, wu:fi19g05 antikoerper, zgc:100936 antikoerper, CRKII antikoerper, p38 antikoerper, Crko antikoerper, crk2 antikoerper, crkII antikoerper, v-crk antikoerper, P38C-CRK antikoerper, Crk-I antikoerper, Crk-II antikoerper, Crk-III antikoerper, Crk3 antikoerper, CrkIII antikoerper, c-Crk antikoerper, Crk oncogene antikoerper, v-crk avian sarcoma virus CT10 oncogene homolog antikoerper, CRK proto-oncogene, adaptor protein antikoerper, v-crk avian sarcoma virus CT10 oncogene homolog L homeolog antikoerper, v-crk sarcoma virus CT10 oncogene homolog antikoerper, Crk antikoerper, crk antikoerper, CRK antikoerper, crk.L antikoerper
Hintergrund
CRK is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.
Molekulargewicht
33831
Gen-ID
1398
NCBI Accession
NP_005197 , NP_058431
UniProt
P46108
Pathways
Neurotrophin Signalübertragung , CXCR4-mediated Signaling Events , Signaling of Hepatocyte Growth Factor Receptor
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