c-MYC Antikörper (pThr58)
(1 reference)-
- Target Alle c-MYC (MYC) Antikörper anzeigen
- c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
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Bindungsspezifität
- pThr58
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser c-MYC Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Dot Blot (DB)
- Homologie
- X, Zf, M, Rat, B, Pig, Sh
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This MYC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC.
- Klon
- RB11187
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product MYC Primärantikörper
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anti-Myc Proto-Oncogene protein (MYC) (AA 330-439) antibody
MYC Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1G7 unconjugated
anti-Myc Proto-Oncogene protein (MYC) (Center) antibodyMYC Reaktivität: Human, Maus WB, IF, IP, ICC, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibodyMYC Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pThr58) antibodyMYC Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibodyMYC Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) antibodyKO Validated MYC Reaktivität: Human WB, IF, ChIP Wirt: Kaninchen Monoclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (AA 101-200) antibodyMYC Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) antibodyMYC Reaktivität: Human ELISA Wirt: Maus Monoclonal 7E10 unconjugated
anti-Myc Proto-Oncogene protein (MYC) (N-Term) antibodyMYC Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pThr358) antibodyMYC Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:1000. DB: 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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-
: "I?B kinases increase Myc protein stability and enhance progression of breast cancer cells." in: Molecular cancer, Vol. 10, pp. 53, (2011) (PubMed).
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: "I?B kinases increase Myc protein stability and enhance progression of breast cancer cells." in: Molecular cancer, Vol. 10, pp. 53, (2011) (PubMed).
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- Target
- c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
- Andere Bezeichnung
- Myc Proto-Oncogene protein (MYC Produkte)
- Hintergrund
- MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.
- Molekulargewicht
- 48804
- Gen-ID
- 4609
- NCBI Accession
- NP_002458
- UniProt
- P01106
- Pathways
- p53 Signalweg, Zellzyklus, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effekt
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