Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

Insulin Receptor Antikörper (pTyr1185)

Name: Insulin Receptor Antikörper (pTyr1185)
SKU: ABIN389937
Price: 467.5 EUR
Availability: InStock

INSR Reaktivität: Human DB Wirt: Kaninchen Polyclonal RB15377 unconjugated

Dot blot analysis of anti-Phospho-INSR-p Antibody (ABIN389937 and ABIN2839751) on nitrocellulose membrane. (Insulin Receptor Antikörper (pTyr1185))

1 image

Produktnummer ABIN389937

Datenblatt (PDF)

Target Alle Insulin Receptor (INSR) Antikörper anzeigen

Insulin Receptor (INSR)
Bindungsspezifität
16

14

13

11

8

8

7

5

5

5

4

4

4

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr1185
Reaktivität
171

88

77

17

12

9

8

7

6

6

4

3

2

2

1

1

1

1

1

1

1

1
Human
Wirt
157

29

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
146

43
Polyklonal
Konjugat
121

15

14

5

5

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Insulin Receptor Antikörper ist unkonjugiert
Applikation
135

77

53

33

20

16

15

15

13

13

8

5

4

4

3

2

2

2

1

1

1

1

1

1
Dot Blot (DB)

Homologie

B, M, Rat, X, D

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This INSR Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1185 of human INSR.

Klon

RB15377

Isotyp

Ig Fraction

Top Product

Discover our top product INSR Primärantikörper
anti-Insulin Receptor (INSR) antibody
INSR Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C19 unconjugated

anti-Insulin Receptor (INSR) (AA 1024-1298) antibody
INSR Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 1027-1364) antibody
INSR Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 1101-1372) antibody
INSR Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Insulin Receptor (INSR) (C-Term) antibody
INSR Reaktivität: Human, Maus, Ratte, Hund, Affe, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Schwein, Huhn, Schaf, Hamster, Avian, Cat, Esel, Ziege WB Wirt: Ziege Polyclonal unconjugated

anti-Insulin Receptor (INSR) (C-Term) antibody
KO Validated INSR Reaktivität: Human WB, ICC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 1325-1358) antibody
INSR Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB50340 unconjugated

anti-Insulin Receptor (INSR) (AA 1023-1298) antibody
INSR Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 51-150) antibody
INSR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 27-57), (N-Term) antibody
INSR Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB1421 unconjugated

Applikationshinweise

DB: 1:500

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

Insulin Receptor (INSR)

Andere Bezeichnung

INSR (INSR Produkte)

Hintergrund

Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake, thereby mediating the metabolic functions of insulin. Binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). This protein can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked.

Molekulargewicht

156333

Gen-ID

3643

NCBI Accession

NP_000199, NP_001073285

UniProt

P06213

Pathways

NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity