ANTXR1 Antikörper (pTyr425)
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- Target Alle ANTXR1 Antikörper anzeigen
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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Bindungsspezifität
- pTyr425
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ANTXR1 Antikörper ist unkonjugiert
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Applikation
- Dot Blot (DB)
- Homologie
- M, Rat
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This ANTXR1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y425 of human ANTXR1.
- Klon
- RB16635
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product ANTXR1 Primärantikörper
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- Applikationshinweise
- DB: 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
- Andere Bezeichnung
- ANTXR1 (ANTXR1 Produkte)
- Synonyme
- ANTXR1 antikoerper, ATR antikoerper, TEM8 antikoerper, 2310008J16Rik antikoerper, 2810405N18Rik antikoerper, Antrx1 antikoerper, Tem8 antikoerper, anthrax toxin receptor 1 antikoerper, ANTXR1 antikoerper, Antxr1 antikoerper
- Hintergrund
- ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
- Molekulargewicht
- 62789
- Gen-ID
- 84168
- NCBI Accession
- NP_060623, NP_115584, NP_444262
- UniProt
- Q9H6X2
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