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Leptin Receptor Antikörper (N-Term)

LEPR Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB02053 unconjugated
Produktnummer ABIN390093
  • Target Alle Leptin Receptor (LEPR) Antikörper anzeigen
    Leptin Receptor (LEPR)
    Bindungsspezifität
    • 16
    • 16
    • 9
    • 9
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-52, N-Term
    Reaktivität
    • 107
    • 71
    • 49
    • 19
    • 12
    • 4
    • 3
    • 3
    Human
    Wirt
    • 110
    • 14
    • 2
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 107
    • 23
    Polyklonal
    Konjugat
    • 48
    • 11
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser Leptin Receptor Antikörper ist unkonjugiert
    Applikation
    • 81
    • 42
    • 36
    • 34
    • 26
    • 25
    • 15
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This Leptin Receptor (LEPR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human Leptin Receptor (LEPR).
    Klon
    RB02053
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product LEPR Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    Leptin Receptor (LEPR)
    Abstract
    LEPR Produkte
    Synonyme
    CD295 antikoerper, LEP-R antikoerper, LEPRD antikoerper, OB-R antikoerper, OBR antikoerper, obr antikoerper, cd295 antikoerper, ob-rb antikoerper, Fa antikoerper, LEPROT antikoerper, Leprb antikoerper, Modb1 antikoerper, OB-RGRP antikoerper, Obr antikoerper, db antikoerper, diabetes antikoerper, obese-like antikoerper, obl antikoerper, ObRb antikoerper, Ob-R antikoerper, Ob-RM antikoerper, lepr antikoerper, leptin receptor antikoerper, leptin receptor S homeolog antikoerper, LEPR antikoerper, lepr antikoerper, Lepr antikoerper, lepr.S antikoerper
    Hintergrund
    Leptin, an adipocyte-specific hormone, regulates adipose-tissue mass through hypothalamic effects on satiety and energy expenditure by acting through the leptin receptor (LEPR). LEPR is a single-transmembrane-domain receptor of the cytokine receptor family that is identical to the mouse diabetes (db) gene product. During weight loss, leptin levels decrease, whereas soluble LEPR levels and the receptor bound fraction of leptin increases. The presence of LEPR in the absorptive cells of the small intestine suggests that leptin may have a physiological role in the regulation of nutrient absorption.
    Molekulargewicht
    132494
    Gen-ID
    3953
    NCBI Accession
    NP_001003679, NP_001003680, NP_001185616, NP_001185617, NP_001185618, NP_002294
    UniProt
    P48357
    Pathways
    JAK-STAT Signalweg, AMPK Signaling, Feeding Behaviour
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